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Drug Intell Clin Pharmacol

Safety and tolerability of inebilizumab (MEDI-551), an anti-CD19 monoclonal antibody, in patients with relapsing forms of multiple sclerosis: results from a phase 1 randomised, placebo-controlled, escalating intravenous and subcutaneous dose study
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2022;11(19) doi: 10.3390/cells11193023

The human genome contains at least 11 million SNPs, about 1% of which are non-synonymous coding SNPs (nsSNPs)

However, in APP/PS1 mice, which develop AD-related -amyloid plaques, periplaque reactive astrocytes exhibit significantly increased GABA immunoreactivity
