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While the clinical trial was extensive enough to gain FDA approval for the treatment, the longest that some patients were observed for risks and side effects was six monthsand that was only a portion of the participants from the clinical study

doi:10.1002/14651858.CD004655.pub3

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Retrieved 8 December 2021

methionine synthase, MCM: methylmalonyl-CoA mutase

Neurological recovery may take 612 months, and some deficits may be permanent if treatment is delayed