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25 Similarly, SigHotSpotter uses a probabilistic Markov chain to infer signaling hotspots from scRNA-seq data, identifying key regulators that stabilize stem cell phenotypes across various tissues, including muscle

Figure 3 4.1 Glucose uptake The metabolic flux of glucose depends on glucose uptake by tumor cells, during which glucose enters tumor cells via active transport

This finding suggests that reduced B 12 bioavailability may lead to reduced mitochondrial methylmalonyl-CoA mutase activity and increased oxidative stress and that specific treatment may rescue mitochondrial integrity

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