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Modulador de expresin gnica de amplio espectro : estudios transcriptmicos (Pickart et al., Biomed Res Int 2015) demuestran que GHK-Cu modula la expresin de ms de 4,000 genes humanos (15% del genoma codificante), reseteando perfiles transcripcionales hacia patrones de tejido joven

Drug discovery 2, 205213, 10.1038/nrd1031 (2003)

The CXXC Motif: a Rheostat in the Active Site

When analyzing our scRNA-seq data, we observed that three additional granin family members: Scg2 (Secretogranin II), Chga (Chromogranin A) and Scg3 (Secretogranin III), were upregulated in cells following glucagon receptor disruption (Supplementary Fig

Understanding astrocyte-specific epigenetic signatures thus represents new avenues for identifying novel biomarkers and developing precision therapeutics targeting glial dysfunction in AD

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