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From the mechanism, iron accumulation in Tfh cells was regulated by the microRNA-21/3-hydroxybutyrate dehydrogenase-2 axis, which also strengthened the Fe (II)-dependent TET enzyme activity and demethylation of the BCL6 gene (119)

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In addition, female genital schistosomiasis has been found to increase the risk of human immunodeficiency virus (HIV) transmission [38]

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