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This study involved only non-invasive application of a test hydrogel on the dorsal hand skin of a healthy adult volunteer for photographic documentation

10.1016/s0896-6273(00)80117-8 101 KovoorP.WickmanK.MaguireC

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Fortified means food producers add in more of a nutrient (such as a vitamin or mineral) than is naturally found in the food

Through the interaction of these receptors, the brain can receive signals of peripheral inflammation and respond through neural signaling, thereby modulating or alleviating the inflammatory response