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Synthetic neoantigens formed by proteasome-resistant modification of KRAS G12C peptides with covalent inhibitors are loaded onto HLAs as so-called haptenated peptides or p* (peptides still carrying the covalent inhibitor) and presented as p*MHCs on the cancer cell surface as homogeneously modified epitopes

Low free and total plasma sulfate in children with autism has been previously reported in two studies [36, 37], and is consistent with four studies [36, 3840] which found that children with ASD had a significantly decreased sulfation capacity compared to controls, based on decreased ability to detoxify paracetamol (acetaminophen)
Physiol., 2010

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