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Available at Last update 07/21/2022

Physiological values of ROS are required to sustain the signaling pathways controlling crucial cellular processes, among which are inflammation, differentiation, proliferation, homeostasis, and apoptosis, whereas the generation of dysregulated ROS can amplify these same pathways, thus fostering disease phenotypes associated with ROS, as seen in type II diabetes, cancer, and atherosclerosis [19]