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doi:10.1136/thoraxjnl-2012-201786

The mode of action and biochemistry of how that happens is a bit too complicated to share here
Key features of heat shock regulatory elements

Management of post-transplant diabetes can be challenging, as immunosuppressive drugs such as glucocorticoids, calcineurin inhibitors, and mTOR (mammalian target of rapamycin) inhibitors are associated with induction of hyperglycemia or worsening of glucose control
Notably, specific sHSPs have evolved to partner with the HSP70 machinery directly