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TB-500 safety data is less extensive but similarly suggests good tolerability in preclinical models

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The initiator of the pathophysiological process has not been elucidated yet, although acute gastrointestinal infections have been found to initiate the symptoms in a certain group of patients with IBS (post-infectious IBS) (81)

For this, we introduced a second copy of gspD under the control of the copper-inducible promoter, P cuoA at the attB site 75 into our clones that had successfully integrated the deletion plasmid

As mentioned earlier, NIS is responsible for this transport [78, 125, 126]

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