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The most serious risk, lactic acidosis, is extremely rare (estimated at 1-5 cases per 100,000 patient-years) and occurs almost exclusively in patients with severe kidney impairment or acute illness

Nat Microbiol 5 , 883884 (2020)

[DOI] [PubMed] [Google Scholar] 8.Di Ciaula A, Garruti G, Wang DQ-H, Portincasa P

"'Shields: Expanded' and 'Shields: B-Sides' are out now"

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