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Most formulations require refrigeration between 2 to 8C (36 to 46F) and protection from light

Reduced shedding tends to come first, followed by visible thickening between month 3 and month 6

Loading phase for cellular repair

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We need more evidence to know if the pills are as effective as the shots over time, though some research suggests they work, especially when it comes to sublingual supps

Some observational research has also suggested a slight increase in lung cancer risk linked to long-term, high-dose B6 and B12 supplementation, particularly among men and smokers, although this kind of study cannot prove that the supplements caused the cancers