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In the pivotal 2018 animal study by Neelakantan et al., systemic treat Mechanism of Action 5-Amino-1MQ inhibits NNMT (nicotinamide N-methyltransferase), an enzyme that catalyzes the N-methylation of nicotinamide using S-adenosylmethionine (SAM) as the methyl donor, producing 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH) as products

The name comes from reported improvements in skin appearance and overall tissue quality

[DOI] [PubMed] [Google Scholar] 11.Hariprasad M, Razdan R

The standard treatment for hyperhomocysteinemia is supplementation with folate, vitamin B6, and vitamin B12

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Fellow of the American College of Surgeons