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GSH deficiency or a decrease in the GSH/glutathione disulfide (GSSG) ratio manifests itself largely through an increased susceptibility to oxidative stress, and the resulting damage is thought to be involved in diseases such as cancer, Parkinsons disease, and Alzheimers disease

Noncoding microdeletion in mouse Hgf disrupts neural crest migration into the stria vascularis, reduces the endocochlear potential and suggests the neuropathology for human nonsyndromic deafness DFNB39

Alarcn et al., 2015)

Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

Van Cauter, E., & Copinschi, G

2012:734125.10.1155/2012/734125 Clin