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The toxic effects of lidocaine can occur in a dose-dependent manner

Rosenwasser, 2001), and there is recent evidence for decreased expression of several circadian clock genes (Huang et al., 2010a) as well as a polymorphism in one of the genes ( Per3 ) that is associated with insomnia severity in alcohol-dependent subjects (Brower et al., 2012)

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LEANGBB, or also known as Gamma-Butyrobetaine, or just GBB

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