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Emerging data suggests metformin may act centrallywithin the ventromedial hypothalamus (VMH)through a pathway involving Rap1
Other common side effects of B12 injections include: Diarrhea Headache Swelling (and not only at the site of the injection) If you experience any uncommon side effects, such as chest pain or hives, contact your health care provider immediately

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For the long-term management of pernicious anemia after B12 replenishment, parenteral treatment with B12 every 13 months seems sufficient to prevent a relapse [13,14,15]

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1 Methylcobalamin occurs naturally in the body and assists in producing red blood cells, DNA and other physiologic functions
