patent tim guilford glutathione CooP | Glioblastoma-Targeting Nonapeptide Chemotherapeutic Potential of Chlorambucil-Platinum(IV) Prodrugs

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Free Radical Biol Med 45(4):357366

172 Contrary to the other substrates that undergo a hydrogen abstraction on the 8 position, the hydrogen abstraction occurs on the 5 position of ALA, creating 12-HOTrE as the main product (Scheme 10)

[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Ralph SJ, Rodriguez-Enriquez S, Neuzil J, Saavedra E, Moreno-Sanchez R

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Our results in TBI mice showed that GFAP levels peaked at 24 h in both vehicle and CAQK-treated groups, indicating comparable severity of TBI