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Preclinical euglycaemic clamp data showed no impairment of insulin sensitivity at therapeutic doses

Semaglutide (Ozempic/Wegovy) is a GLP-1 receptor agonist that suppresses appetite

doi: 10.1084/jem.20041061

In the U.S., it's lumped in with dietary supplements, not meds, so the FDA doesnt really oversee the details
