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Anti-myeloma activity of a novel glutaminase inhibitor CB-839

Trimethylamine N-Oxide aggravates liver steatosis through modulation of bile acid metabolism and inhibition of farnesoid X receptor signaling in nonalcoholic fatty liver disease

These results are consistent with results observed in mice (26) and strongly support a role for gut microbiota in BB generation from dietary l-carnitine in humans

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Vogl D, Hari, MR, Jones SS, Supko JG, Leone G, Wheeler C, Orlowski RZ , Richardson PG, Lonial S, Tamang D, and Jagannath S