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Upstream signals are sensed by GSH and, depending on the GSH buffering capacity, transmitted into a downstream response

British Journal of Nutrition , 108 (7), 12721279

doi: 10.1073/pnas.1117280109 139 GraybillJ

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S., and Branco L

IDE-397 is another MAT2A inhibitor with low hepatotoxicity and high solubility that has shown potent modulation of SAM and symmetric dimethyarginine (SDMA) in preclinical studies
