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XML reduced Beclin 1 and Atg7 accumulation, upregulated protein kinase B (PKB)/Akt, PI3K, and Bcl-2 levels, and inhibited autophagy to alleviate cardiomyopathy (146) (Figure 5)
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However, there are only few published studies that describe the effect of APAP per se on the CNS in the absence of ALF
