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Petersburg Institute of Bioregulation and Gerontology, primarily under the direction of Vladimir Khavinson

PMID: 22950504

Activation of the kappa-opioid receptor (KOR) significantly decreases dopamine release in mesolimbic pathways by reducing the firing of dopaminergic neurons and presynaptic dopamine release in the nucleus accumbens

Indications and Usage for B-12 Compliance Injection Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see DRUG INTERACTION), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue

& Nelson, R
