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(2020) Local administration of methylcobalamin for subacute ophthalmic herpetic neuralgia: a randomized, phase III clinical trial

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Restless Leg Syndrome is difficult to treat for several reasons: Complex and Varied Causes: The exact cause of RLS is not fully understood, but it is believed to involve a combination of genetic, neurological, and environmental factors

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These symptoms can sometimes discourage patients from continuing their treatment
