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Chen Zhiyi of Nanhua University and others designed a kind of ultrasound-responsive bacteria, which can induce the expression of foreign gene IFN- in an ultrasound-controlled way, and improve the anti-tumor efficacy of the engineering bacteria in vitro and in vivo (42)

10.1371/journal.pone.0046599 [DOI] [PMC free article] [PubMed] [Google Scholar] Rapado-Castro M., Dodd S., Bush A
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Specifically, the landmark study demonstrated that mice treated with AX exhibited significant activation of AMPK, a kinase sensitive to cellular energy levels that coordinates metabolism and promotes mitochondrial energy production
