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Cell Microbiol 6:201211 Grokinsky DK, Koffler BE, Roitsch T, Maier R, Zechmann B (2012) Compartment-specific antioxidative defence in Arabidopsis against virulent and avirulent Pseudomonas syringae

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Activation of Nrf2 can prevent BAPN-induced AD by impeding ROS-mediated activation of the NLRP3 inflammasome, concurrently diminishing the invasion of macrophage and production of MMPs and pro-inflammatory cytokines (166)

As tesaglitazar decreased SIRT1 expression and increased Ac-PGC1 levels, we assessed whether pharmacological activation of SIRT1 by resveratrol and eventually PGC1 would alleviate cardiac toxicity driven by dual PPAR/ activation