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In NASH patients, an increased activity of CYP2E1 (41) has been also observed, an important microsomal source of OS, especially together with C47T polymorphisms of SOD2 (encoding MnSOD) (4145)
Drug Metab Rev 44(4):267286
[Google Scholar] 117.Tilkens MJ
& Padmanabhan, V
Of the 9 PCs, 7 are secreted or shed, and are possible candidates for cleaving IGF-I outside of the cell
Wen J, Chen H, Ren Z, et al
