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The IL-1 level indicates the activation of the inflammatory cascade, while the levels of IL-6 and TNF- are known to mediate and amplify inflammatory processes

doi: 10.1007/s13197-018-3035-z, 192 XieY.PanM.GaoY.ZhangL.GeW.TangP
10.3233/JAD-220224 56 KnyszyskaA.RadeckaA.ZabielskaP.uczakJ.KarakiewiczB.LubkowskaA
Your lifestyle choices can speed up collagen loss beyond normal aging

FIGURE 1 To go deeper and understand if a protective mechanism might contribute to modulate the phenotype in this family, here, we report the results of the analysis of redox gene expression profiles in leukocytes and fibroblasts of all family members, particularly focusing on the nuclear factor erythroid 2-related factor 2 (NRF2) and on its glutathione (GSH)-related target genes
[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Fetisova E., Chernyak B., Korshunova G., Muntyan M., Skulachev V