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Less common and even rarer side effects include: depression, loss of urine control, diarrhea, unpleasant odors, behavioral changes, fast heartbeat (palpitations), dizziness, passing out, excitability, anxiety and severe headaches

The study population characteristics were: median age of 64 years (range: 34 to 84), 49% age 65 years or older, 59% male, 94% White and 3% Asian, and 18% with history of brain metastases at baseline

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