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Thus, lncRNA GDIL is a novel target to promote GSH degradation and augment platinum therapy

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the B-Complex Injection can help mitigate drug-induced B deficiency, but the clinician should be mindful to coordinate its use so that adequate B is maintained without causing excessive levels

Interestingly, one of the newly introduced cysteine residues (Cys-207) apparently forms an intermolecular disulfide bridge in the crystal (Supplementary Figure S2), which may promote crystallization

Importantly, GLPs exert gut-heart axismediated benefits by selectively enriching SCFA-producing bacterial taxa, boosting colonic SCFA bioavailability, and suppressing hepatic TMAO synthesisthereby mitigating key drivers of diabetic cardiomyopathy progression