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Another report documented that lymphocyte function-associated antigen 1 (LFA-1) requires magnesium to adopt its active conformation to mediate signaling in T cells, which in turn increases calcium flux, leading to perturbation of cell signaling downstream

2.2.1 Inflammatory cells Through interaction with pro-inflammatory cells, such as macrophages, neutrophils, and lymphocytes, as well as non-cellular components, cancer cells aid in the production of the inflammatory TME

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the peptide has the potential to induce a wide range of responses from growth stimulation to toxic cell differentiation

81 Because mtDNA exists in multiple copies, two scenarios are possible: homoplasmy, where all mtDNA copies are identical, or heteroplasmy, where the copies differ

Zenner 1999