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Studies indicate that the lifetime risk of CRC in individuals with PMS2 mutations ranges between 10% and 20%, significantly lower than that of MLH1, MSH2, and MSH6 mutation carriers ( PMS2 carriers is estimated to be between 12% and 15%, also lower than those associated with other MMR genes

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RTKi = receptor tyrosine kinase inhibitor

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Why Athletes Are Especially Vulnerable to Glutathione Depletion The Demands of Modern Training Competitive and serious recreational athletes train at very high volumes that consistently stress their body's antioxidant systems
