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Final report of phase II study of sorafenib, cytarabine and idarubicin for initial therapy in younger patients with acute myeloid leukemia

ScienceDirect , Lo, Chih Hung

It should be noted that not only GSK3, but also other kinases, such as AMP-activated protein kinase (AMPK) and mechanistic target of rapamycin complex 1 (mTORC1), directly or indirectly regulate Nrf2 stability and activity (Silva-Islas and Maldonado, 2018)

Food and Drug Administration: Washington, DC, Pitkin RM

However, AMPK is also able to phosphorylate (activate in this case) the OGT at Thr 444, which in turn could lead to O-GlcNAcylation of AMPK, resulting in a complex regulation that involves changes in the activities of enzymes as well as their cellular localizations ( FIGURE 6 Glutathione, as discussed above, has an important antioxidant role in neurons

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