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Furthermore, circulating IGF-1 has been shown to be a critical vasoprotective factor that declines with age, and its deficiency can accelerate vascular aging [165]

10.1038/s41598-019-40913-y 241 YamashitaS.Tsubakio-YamamotoK.OhamaT.Nakagawa-ToyamaY.NishidaM

Samples were aliquoted into fractions of plasma, serum, erythrocytes, and buffy coat and stored under liquid nitrogen at 196 C

Abstract Purpose Hyperglycemia causes abnormal accumulation of methylglyoxal (MGO) and concomitant DNA, protein glycation

Recent Adv Prolact Res 2015:243264 Brand JM, Frohn C, Cziupka K, Brockmann C, Kirchner H, Luhm J (2004) Prolactin triggers pro-inflammatory immune responses in peripheral immune cells

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