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doi: 10.1016/S1470-2045(07)70203-6

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More significant changes, such as improvements in body composition and muscle tone, typically become more apparent after two to three months of consistent use

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In contrast, DIO mice in both groups switched from WD to LD each had significantly increased Proteobacteria relative abundance (represented solely by the genus Parasutterella ) compared to both the WD and the LD controls, suggesting that Proteobacteria relative abundance may be largely influenced by stress or the differences in net energy expenditure (or associated body weight changes) caused by the diet switch

1 Vitamin B 12 levels greater than 350 pg per mL seem to be protective against symptoms of vitamin B 12 deficiency