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Conversely, HIF1 recruits RORt and p300 to the Il17a promoter, thereby transactivating Il17a expression and promoting Th17 cell differentiation

71 Interestingly, metabolite profiling of cells treated with Cu ionophore presents a time-dependent increase in the dysregulation of many TCA cycle-associated metabolites, and inhibiting the electron transport chain complexes I and II significantly reduced Cu-induced cell death

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We ignore other reactive oxygen species besides H 2 O 2 , or, put a different way, H 2 O 2 represents them all

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