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Therapeutical interventions that aim to increase GSH concentrations in vivo include N -acetyl cysteine

For instance, in several clinical and preclinical studies, SF counteracts several molecular abnormalities associated with autism spectrum disorder (ASD) that address reduced antioxidant capacity, enhanced oxidative stress, deficient glutathione synthesis, mitochondrial dysfunction, increased lipid peroxidation, and neuroinflammation (2)

doi: 10.3390/BIOLOGY10111123 101 KhanM

Cot, J

The chief organisms capable of its synthesis are fungi and certain yeasts (59,60) , though actinobacteria and certain other micro-organisms (6066) , including the slime mould Physarum polycephalum (65) , cyanobacteria (6771) and methylotrophs (72) are also naturally capable of its production

The potential for glutathione to minimize or reduce free radicals is apparent from the reported changes in glutathione status after exercise