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Oral administration of meclofenoxate to rats (100 mg/kg, daily for 37 days) significantly improved memory impairment, and reduced neuronal damage, proinflammatory mediator levels, and oxidative stress to normal levels

Laird, M

Were talking 4x more mice reaching 23 months

Exercise and PT Exercise is essential for everyone with arthritis, but its even more vital in AS, especially if you have high disease activity

Occludin, claudin-5, and claudin-8 were found to be downregulated and redistributed, whereas claudin-2 (pore-forming TJ protein) was strongly upregulated

Mayo Clinic Proceedings: Innovations, Quality & Outcomes