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Abstract Male late-onset hypogonadism is an age-related disease, the core mechanism of which is dysfunction of senescent Leydig cells
The published skin-appearance studies almost all use topical creams and serums applied to the skin surface
no clinical trials validate the combination
It is found in the body and plays an important role in tissue repair, collagen production, and cellular regeneration
The seeds are numerous, irregularly round, and flat with a pale-yellow aril (Zhang et al., 2018)
