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they can serve as reducing or oxidizing agents by taking an electron from another molecule or giving it to them (Cheeseman and Slater, 1993

PMID 33592356 72 Shin HK, Grahame G, McCandless SE, Kerr DS, Bedoyan JK

Biochim et Biophys Acta (BBA) - Gen Subj Tsagris V, Liapi-Adamidou G

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Our data indicate that endogenous electrophilic stress accumulation in the nucleus is predominantly sensed and managed by the large subunit of the CBC, NCBP1, resulting in rapid suppression of translation approximately 2 hours after nuclear-localized electrophile buildup

On the one hand, the activation of endoplasmic reticulum stress pathway in cancer cells can inhibit ferroptosis and participate in the induction of drug resistance