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Nevertheless, emerging data allow us to propose that severe hyperhomocysteinemia might primarily have homocysteinylation effects related to homocysteine and/or its by-products (as homocysteine thiolactone) that would affect the vascular wall structure through a mechanism independent of an oxidant stress

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The information presented here is based on preclinical research, primarily animal studies, and should not be construed as medical advice

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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Vitamin B12 intake from animal foods, biomarkers, and health aspects

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Pevec et al., 2010) and worsening, and immunosuppression (Sikiric et al., 2003)

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