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In human cells, siRNA-mediated silencing of ISCU resulted in increased IRE-binding activity of IRP1 and IRP2 and increased IRP2 protein levels [23]

Time trials have greater logical validity compared to time-to-exhaustion tests [23]

Given the heterogeneity in synaptic targets and specific features of the different subclasses of GABAergic neurons, altered interactions between different GABAergic neurons and pyramidal neurons may influence neuronal activity and hence functional output in different manners

Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol

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