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doi: 10.1016/j.bbaexp.2005.03.003

Freezing causes ice crystal formation that physically destroys the peptides three-dimensional structure

In chronic stress models, semax reduced corticosterone spikes and normalized HPA axis markers

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In one experiment, fetal transplants into the striatum of PD patients showed protein inclusions that closely mirrored LP, demonstrating that aSYN pathology moved from the host into the graft [27]

This, in turn, can enable delivery of drug cargo in the target cell within the brain parenchyma