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Methods In this research, we performed a two-step Mendelian randomization analysis by utilizing genome-wide association study (GWAS) data obtained from MiBioGen and UK Biobank

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Importantly, we find that the ISR pathway is required for efficient epithelial cell differentiation and lytic EBV reactivation in NOKs and show that expression of CHOP alone is sufficient to induce lytic EBV reactivation and differentiation

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