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doi: 10.1007/s10571-023-01388-8 36 WangBWangYZhangJHuCJiangJLiYet al

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(2021) found that inhibition of the PI3K/Akt pathway suppressed the activation of Nrf2 by hesperetin and eliminated the reduction in excessive ROS production induced by hesperetin [52]

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