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[2] Pharmacokinetic studies demonstrate rapid systemic distribution with peak plasma levels occurring within 30-60 minutes of intramuscular injection, followed by extensive hepatic storage and enterohepatic recycling

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Cobalt Allergy and a Risk Vitamin B12 Hypersensitivity Due to the fact that vitamin B12 contains cobalt as the central atom of the molecule, the problem of hypersensitivity to cobalamin may also particularly concern people allergic to cobalt [86,87]

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