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China Patent Application CN102134556 (A) Richie JP, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE (2015) Randomized controlled trial of oral glutathione supplementation on body stores of glutathione

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This drop can be largely explained by 1) the overactivation of IDO-1 shunts the available TRYP into KP, increasing KP metabolites, depleting serotonin, and causing mood disorders and other related neurological symptoms