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Furthermore, increase in expression and activity of Nqo1 was found in astrocytes and neurons of AD brain along with predominant cytoplasmic localization of Nrf2 in AD hippocampal neurons [71]

Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistance

Future research should focus on overcoming these shortcomings

doi: 10.3390/ijms26104526 Summary Keywords Chronic Obstructive Pulmonary Disease, metabolic reprogramming, inflammation, oxidative stress, airway remodeling, immunometabolism Citation Zeng S, Zhang Y, Li S, Li Z, Li P, Xie J, Zhang J, Xie L and Yang Y (2025) From metabolic alterations to chronic inflammation: mechanisms and immunoregulation of metabolic reprogramming in COPD

[DOI] [PubMed] [Google Scholar] 9.Alagawany M., Ashour E.A., El-Fakhrany H.H.H., Ismail T.A., Nasr M

In summary, the HPA axis is a key component of the MGBA, and a possible mechanism is that VNS modulates PD-related neuropsychiatric symptoms by regulating HPA axis function via the vagus nerve
