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Figure 1 At the taxonomic level, demyelination was associated with an increased abundance of the phylum Firmicutes and reductions in Verrucomicrobiota and Actinobacteria ( Figure 1C ), which appeared to revert upon toxin withdrawal

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The IL-17-mediated liver inflammation and fibrosis are noted as being similar to those in PSC

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Sustained activity of DRP1 causes macrophages to exhibit proinflammatory activity even in the absence of LPS, whereas loss or inhibition of DRP1 attenuates M1 polarization