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Nevertheless, a molecular understanding of how the infection modulates bacterial compositions in distant organs is urgently needed

these bioactive molecules act on multiple targetsincluding EMT-related transcription factors and key signaling cascadesto effectively block epithelial-mesenchymal conversion, suppress myofibroblast activation and regulate aberrant extracellular-matrix (ECM) remodeling, thereby markedly curbing EMT progression and fibrotic disease ( Triptolide (TP), an active diterpenoid extracted from Tripterygium wilfordii Hook F, possesses anti-inflammatory, antiproliferative and immunomodulatory properties, and has been widely investigated in experimental idiopathic pulmonary fibrosis (IPF) models in recent years ( Total saponins of Astragalus membranaceus (ASTs) are the principal active constituents isolated from Astragalus membranaceus

Non-oncogene addiction of KRAS-mutant cancers to IL-1beta via versican and mononuclear IKKbeta

Both peptides have positive effects on cardiac (heart) muscle

Modified enzymes that simultaneously cleave IgM and IgG have been reported to reduce antibody neutralization and complement activation during AAV gene transfer