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520 The anti-tumor effect of liraglutide is related to its inhibition of the PI3K/Akt signaling pathway, as the activation of Akt is crucial for promoting cell survival and proliferation, and liraglutide can inhibit this process in a dose-dependent manner

Using an ex vivo granuloma explant model, this study identified clemastine, an antihistamine drug, to reduce the mycobacterial growth within complex established granulomas through potentiation of the purinergic receptor P2RX7 (42)

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